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PMID: 20080680

One reason for the difference is that rats lack cultural inhibitions that we humans have, says Pfaus

In a pooled analysis of two retrospective, observational studies (including the phase 3b study [11]), plasma ammonia levels were reduced to a significantly greater extent with carglumic acid + ammonia scavengers than with ammonia scavengers alone at all timepoints during the first 72 h of treatment, except 1224 h (Table 3) [12]